It's a meta-commentary by Scorcese on his entire career. The bad guys were always relatable. Sure they kill people and do "bad guy" things, but we like them. Not here. The characters are repulsive right from the start. We're immediately filled with dread for what's to come. Unlike his past films, Scorcese makes this one about the victims, about the consequences of the killings, about societal indifference and racism and above all about greed. Greed has been a driving force in many of Scorcese's films, but here it's shown in all its horror. Scorcese has a cameo in the final scene that sums it all up very briefly, simply and appropriately. I won't spoil it, but it left me speechless. I couldn't get out of my seat when the credits rolled and it took me until the end to collect myself and walk out, because it wasn't just about this tragic story, but about all violence and crime . . . and greed.