Cloud Atlas is a masterpiece for those interested in life, morals, and what it means to be human. It is the intertwining of multiple protagonists from different times and very, very separate lives.
If you're interested in emotional rollercoasters and finding yourself as a small speck in the grand universe, then this is the movie for you. For me, it belongs with titles like Benjamin Button, Bicentennial Man, and Doctor Who specials. If you're interested in anime or manga, you may even look towards CLAMP's Tsubasa Chronicles.
"Our lives are not our own. We are bound to others past and present. And by each crime and every kindness, we birth our future." -Sonmi~451, Cloud Atlas.
"I believe there is another world waiting for us, Sixsmith, a better world. And I'll be waiting for you there" -Robert Frobisher, Cloud Atlas.
"I believe death is only a door. One closes, and another opens. If I were to imagine heaven, I would imagine a door opening. And he would be waiting for me there." -Sonmi~451, Cloud Atlas.
"What is an ocean but a multitude of drops?" -Adam, Cloud Atlas.