It's a good show. I think you should give it a shot if you're into sci fi dramas with comedic elements.
However... I've watched Joss Whedon's "Dollhouse" in its entirety. And that show changed how I think about this kind of topic. I now feel that if you were to have your brain scanned and be uploaded to a computer-simulated world, the program resulting from such a brain scan would most surely not be you. You're still dead. At best, you'd have a cloned AI program having a jolly good time in an artificial paradise while you rot in the ground (or go to heaven or w/e else you may believe happens when you die). But most assuredly you, the REAL you, would not be linked up to this program. The real you would be worm food.
This realization taints my enjoyment of this show. It's the same reason I could never get into the show "Altered Carbon" - an AI copy of you isnt really you. If this fact ruins UpLoad for you too, go watch dollhouse :P Cant recommend it enough. If it doesnt taint anything for you, then this show is honestly pretty great.