In this era of formula sitcoms that go nowhere and hardly evoke a chuckle...B Positive stands out as innovative, funny, heartwarming, relevant, well-written and superbly acted. Ashford is a rising superstar with innate comedic timing, plenty of acting savvy, and she's a looker to boot. Middleditch plays his role perfectly and there's a magnetic connection between them that can having plenty of storyline. The rest of the cast is great as well. This show has great potential for a long run.