The movie displays interesting ideas about the future after the earth is no longer a proper ecosystem for the human population.
However, the movie did not make more sense. Is it realistic to genetically modify individual and then try to eliminate them as soon as they become a public threat in an experiment worth an investment of not less than 300 million dollars?
Furthermore, too much attention was given to the conflict within the project and yet the main concept appears not to have been touched. The main idea of having a creature who gets information from titan so that the earth inhabitants start moving there, was not really explored. The clinical trials that was conducted appears but totally unrealistic. All the experiments appears to have taken place within one to three years.
Finally, the way the movie ends suggests the need for a titan II, whereas the movie should have ended without such a perspective. The movie should have been whole in itself like the matrix 1. The script should have been better. One question I ask myself is whether the movie was done with a specific end in mind.