The big C has a lot of good things, but is also flawed. The writing was so bad in general that it was almost unwatchable. I strongly disliked every single character; apparently they were supposed to come off as quirky, real, flawed, but ultimately good. They were all redeemed in season 4, but their behavior during the latter half of season 1 as well as seasons 2 and 3 was not believable nor sympathetic. In general, too much drama was packed into every single episode and thus the writing devolved from realistic to melodramatic in order to pack it all in. For the main character, being ill was used as an excuse to be selfish, cruel, rude, insensitive, and so completely self-absorbed as to lack empathy for anybody else. It felt like the audience was supposed to applaud the main character's 'courage' and 'bravery' for not caring what others think but she came across as so unlikable until season 4 that it was hard to feel any sympathy or human connection. And the dialogue overall was simply not believable, and seemed to be intended to create problems and overwrought drama drama drama rather than be a realistic portrayal. The good things about the series were the actors who were first-rate all-around despite having to voice insipid dialogue much of the time, and having to constantly portray extreme highs and lows that came to be tiresome. Another big plus for the series is simply having it be about cancer and how it affects everyone, even if the behavior of the characters didn't track much of the time. Another plus were the guest stars who are outstanding. And there were several bright spots in seasons 1, 2 and 3 despite the flaws. However, the swearing, the disrespect, the sex and nudity often felt disingenuous, having been included for shock value to entice viewers who might otherwise have balked at watching a show about cancer. I would give it 2 and 1/2 Stars, which is a reflection only of the writing and the densely melodramatic plots of each episode rather than a reflection of the superb acting.