I really like Tusk. (spoiler alert)
Wallace foregoes much of his own emotional-psychological humanity, then finds those changes mirrored in the physical alterations forced upon him. His arrogance blinds him to the dangers of his host, who delights in gradually stripping him of what little humanity he has left. Johnny Depp provides the comic relief, but the 2 main characters ultimately get what they believe they deserve, and that is more interesting than "saving" either.