Take everything you know about space travel, engineering, medicine and command structure, fold it up and put it away.
Having said that, the idea of the story is interesting. Plausible? No. Interesting, yes.
Aside from the general over-acting and a tendency for melodrama, the show suffers from pacing issues. Some scenes are exhaustingly long and others miss the mark because they're too short.
Now that I know what to expect, I would watch a second season, especially if they iron out some of the pacing issues.