This is a superior thriller and suspense film from iconic director John Sturges who had a history of making many classic westerns. The story, while labeled science fiction, is plausible and could possibly happen. In a secret laboratory somewhere in the dessert, a team of scientists, working on chemical warfare, develope a toxic virus which, if released, has the potential to kill all life on Earth. The virus is stolen by a madman who holds the world hostage. Cast is uniformly excellent, headed by George Maharis, Richard Basehart, Anne Francis and Dana Andrews. Veteran character actor John Anderson also makes an appearance as does "Star Trek" legend James Dohann. Filmed in wide-screen and color, it also is benefitted by a great music score by Jerry Goldsmith.