My god, what a game!
I've never played anything so bleak and unforgiving.
The narrative of not being able to save everyone and having to make difficult choices, all the while trying not to die from hunger because food costs a fortune because of a sudden economic crisis due to a plague that you're also not trying to catch and die from while time is not your friend, is absolutely depressing for all the right reasons.
It's unlike any game I've played, and I can't recommend it enough if you want to punish yourself.