Few shows can affect you deeply, The Wire for me. Dopesick is another.
It won't raise your heart, it is certainly not a heartlidting experience but nonetheless is a must watch. It is particularly relevant to the normal, hardworking people of the US. Where there is a complete breakdown of regulation and a complete thirst for profit, this what ensues. Death, pain, suffering on one side and money, lies, more money, cover ups and even more money.