Second favorite Resident Evil behind re4 and right in front of the re2 remake (which does justice to the original I grew up on on Gamecube btw). Didn't play 6 honestly but personally I didn't care much for 5, too much of an action shooter. But this - THIS - freaked me the hell out. So so good and so much fun. In regards for lore...
*SPOILER WARNING*
It wasn't connected to the RE universe and Umbrella until 3/4 in, and that didn't bother me but if you're hardcore I can see why it would it annoy some, but still the puzzle and item box aspects and stuff are still there plus AWESOME bosses!