The show mostly revolves around Hank Moody, a writer, and how he struggles in his professional and personal life. He is in love with Karen, and considers her to be her soulmate and he always gets back to her. He has a love for women and almost magically women are drawn to him and this causes many problems for his relationship with Karen and his daughter Rebecca.
There are a few extremely funny moments. While the punchlines could have been improved to make it even funnier, the situations almost always manage to spark a laughter.